Low Basophils Count

Low Basophils count is also known as Basopenia. It occurs when the Basophils count drops to lower than 20 cells/µL of human blood.

The normal white blood cell count of the Basophil ranges between 100 cells/µL in infants to 40 cells/µL in adults. Since the counts are very low, differential white blood cell counting method is more effective in recognizing alternations to normal Basophil counts.

Low Bashophils count may be a result of Leukopenia causes.

Low Basophils count can also be a sign of overwhelming infections, shocks, and Adrenocortical Stimulation.

Low Basophils count is also caused by terminal Urticaria and it can be a sign of ovulation in females.

Low Basophils Count can be also caused by drugs that suppress the immune system.

 

Low Eosinophils Count

Low Eosinophils Count is also known as Eosinopenia, it occurs when the Eosinophils count is less than 50 cells/µL of human blood.

The normal white blood cell count of Eosinophils range between 450 cells/µL in infants to 200 cells/µL in adults.

Low Eosinophils count may occur due to the same causes of Leukopenia such like aplastic anemia and HIV.

Eosinophil is also reduced in the circulating blood in cases of Severe Infections, Shocks, and Adrenocortical Stimulation.

Eosinopenia is also a sing of stress and Cushing’s Disease since the Eosinophils are reduced due to the presence of Adrenocortical Hormones such like cortisol and aldosterone. Treatments with corticosteroids is also a cause of low Eosinophils count for the same reason.

 

Leukopenia

Leukopenia means the “white reduction” and it is a term used to refer to the low white blood cells count.

Since Neutrophils make up the highest count of White Blood Cells, a significant decrease in the normal Neutrophil count (Neutrophilia) would cause a decrease in the normal White Blood Cell Count. The first thoughts that come in mind about a significant decrease in the white blood cells would be associated with a decrease in the Neutrophil (Neutrophilia) and that may cause terms Neutrophilia and Leukopenia to be used interchangeably to give the same meaning, which is absolutely inaccurate. Continue reading “Leukopenia” »

 

Neutropenia

Neutropenia is the decrease to the normal Neutrophil count. Neutropenia is defined as the Neutrophil count that less than 2,500 cells/µL.

The normal white blood cell count for the Neutrophil is 8870 segmental (mature) cells/µL in newborns which drops down dramatically within 2 weeks to lower than 2600 cells/µL, then the normal Neutrophil count starts to increase again to reach 3800 cells/µL in adults.

Since the Neutrophil makes up the majority of white blood cells, except at early childhood, a massive decrease in the Neutrophils count (severe Neutropenia) would cause a noticeable decrease in the total blood cells count (Leukopenia) and sometimes the terms Neutropenia and Leukopenia may be used to refer to each other. But Neutropenia is just a subtype of Leukopenia.

Neutrophils are decreased in the circulating blood by exposure to radiation and Neutropenia is considered as a side effect to Radiation Therapy. Continue reading “Neutropenia” »

 

High Lymphocytes Count

The normal white blood cell count of Lymphocytes for newborns is 5,800 cells/µL. Lymphocytes count increases during the first year to 7000 cells/µL then it starts decreasing to reach 2500 cells/µL in adults.

 

Since Lymphocytes count increases during the early childhood, Lymphocytosis detection varies by age. For children from birth to 3 years old it is defined as the count of 9000 or more Lymphocytes/µL. From 4 to 12 years old, the threshold value is 7000 cells/µL, and 4000 cells or more per microliter for adults.

 

Abnormal increases in the Lymphocytes count can be caused by the same causes of Leukocytosis.

 

High Lymphocytes Count or Lymphocytosis can be cause by viral disorders such like Mumps, Rubella, Rubeola, Hepatitis, and Varicella.

Lymphocytosis occurs as a result of pertussis and Chronic Lymphocytic Leukemia.

 

Monocyte count

Monocyte count represents the number of Monocytes in a microliter (cubic millimeter) of peripheral blood.

The normal white blood cells count of the Monocyte is 1100 cells/µL in infants which decreases to half that count at the first year. In adults the normal count is 300 cells/µL.

High Monocyte Count or Monocytosis is defined as the count of monocytes that exceeds 750 cells/µL in children or 500 to 600 cells/µL in Adults. The count can be increase due to the causes of Leukocytosis.

Monocytes work on fighting non-pyogenic bacteria (bacteria that doesn’t cause Pus) and Monocytosis occurs as a result of infections that caused by non-pyogenic bacteria such like active tuberculosis, subacute bacterial endocarditis, syphilis, and brucellosis.

Monocytosis can also be seen during recovery from cancer, collagen disease, agranulocytosis, and hematologic disorders.

 

High Basophils count

High Basophils count is also known as Basophilia or Basophilic Leukocytosis. High Basophils count is defined as the Basophil count that is greater than 50 to 100 cells/µL of blood.  The case is detected when the Basophil count exceeds 2% of the differential white cells count.

The normal white blood cell count is very low and it range between 100 cells/µL in infants to 40 cells/µL in adults. Since the normal white blood cell count of Basophil is very low, recognizing the alternations on the normal Basophils count based on the absolute number of cells would be very  difficult. And this is why differential white blood cells count method is more effective in observing alternations on the Basophil count.

Beside the causes of Lukocytosis, High Basophils count can occur as a result of some skin diseases, myeloproliferative disorders, chronic granulocytic leukemia, and ulcerative colitis in occasional cases.

 

High Eosinophils Count

Eosinophilia or Eosinophilic Leukocytosis is defined as an Eosinophil count that exceeds 500 cells/µL of blood.

The Normal White Blood Cell count of the Eosinophil ranges between 25,80 cells/µL in infants to 200 cells/µL in adults.

Beside the common causes of Leukocytosis, High Eosniophils count can occur as a result of  parasitic infection.It can also be caused by allergic reactions, pulmonary disorders, skin diseases, and cancer.

 

Neutrophil Count

Neutrophil count is the count of neutrophil white blood cells in a microliter (cubic millimeter) sample of peripheral blood.

Neutrophil makes up the highest count of normal white blood cell count, except at early childhood. Infants are born with the highest neutrophil count, normal Neutrophil count of newborns is 8870 cells/µL. Within the first 2 weeks after birth, the Neutrophil count drops dramatically and then it starts to increase again to reach 3700 cells/µL.

In early childhood, the Lymphocytes count increases to exceed the Neutrophils count, then the Lymphocytes count will start decreasing by aging leaving the majority to the Neutrophil again. Continue reading “Neutrophil Count” »

 

Causes of Leukocytosis

Luekocytosis literally means abnormal increase in the Leukocytes or the white blood cells. Luekocytosis can be affirmed by if the number of leukocytes that are circulating in the peripheral blood exceeds the Normal White Blood Cell Count of 10,000 white cells per microliter.

As production and release of white blood cells is expected in cases of fighting foreign microorganisms that attempt to invade the body. Luekocytosis can also be caused by disorders in the immune system and by bone marrow tumors.

An increase in the Granulocytes (white blood cells with large granules in their cytoplasm) is noticeable during pregnancy. This increase gets more exaggerated during the labor and the first postpartum week. Continue reading “Causes of Leukocytosis” »